Anti-irritating Cosmetics Ingredient PMSoothe® Kava-Oil Introduction
In recent years, the appearance of sensitive skin has become more and more frequent, which significantly affects people’s life quality and increases their psychological pressure and anxiety. Sensitive skin has now become a health issue of global concern. According to the data of China Sensitive Skin Diagnosis and Treatment Expert Consensus, the proportion of Chinese women with sensitive skin is about 36.1%, which means that one out of three people has sensitive skin.

The current mainstream anti-irritation target is TRPV1. The TRPV family responsible for sensing external stimuli in the human body comprises six known members, ranging from TRPV1 to TRPV6. If an anti-irritation ingredient only targets TRPV1, it is highly likely to be ineffective against other TRPV receptors, thereby failing to comprehensively address the diverse irritants encountered by the skin. The market needs a novel anti-irritation mechanism that not only synergizes with the TRPV1 target but also inhibits irritation signals triggered by activation of all TRPV receptors.
Therefore, after many years of in-depth research by Plamed, it was found that Kava Pepper Root Extract is able to directly affect the transmission of stimulus signals-AP generated by the activation of various TRPV receptors through a novel mechanism of action. It has a broader and more reliable anti-irritating effect.
We already have PMSoothe® Kava97 (water soluble powder), it is highly popular in the cosmetics market due to its anti-irritation, skin repair, and anti-wrinkle properties. Some customers want oil-soluble kava extract, so we develop PMSoothe® Kava-Oil.

| Product name | PMSoothe® Kava-Oil |
| INCI name | PIPER METHYSTICUM ROOT EXTRACT, CAPRYLIC/CAPRIC TRIGLYCERIDE |
| Actives content | Kavain≥8000ppm Yangonin≥1500ppm |
| Solubility | Oil soluble |
| Recommended dosage | ≤10% |
| Function | Anti-irritation |
| Highlights★ | Superior ingredients for sensitive skin with strong anti-irritation and repair properties |
