Palmitoyl Pentapeptide-4
Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.
Palmitoyl Pentapeptide-4
Palmitoyl Pentapeptide-4 is a premium active ingredient series developed by Plamed Green Science Group. Derived from natural botanical sources, the products are standardized for highly purified actives and designed to target specific skincare concerns through advanced formulation science.
Overview
Palmitoyl Pentapeptide-4, also known as pentapeptide or base peptide, is a classic signaling peptide composed of palmitic acid and five amino acids. It is widely recognized as a benchmark ingredient for collagen stimulation in the anti-aging industry. Currently, the compliant production of cosmetic-grade Palmitoyl Pentapeptide-4 is primarily produced via chemical synthesis. Plamed employs a peptide synthesis method to manufacture this ingredient, enabling the stable production of a highly active, pure powder product with purity ≥98.0% HPLC and a measured active peptide content of ≥91% (industry-leading). It features extremely low levels of inactive impurities (acetic acid/water), strong batch consistency, and offers the core advantages of high activity and high compatibility; Additionally, the product requires storage at only 2-8°C, eliminating the need for a -20°C ultra-low temperature cold chain, which significantly reduces warehousing and transportation costs. Core biological activity of Palmitoyl Pentapeptide-4: It precisely mimics the C-terminal signal sequence of Type I collagen, activating collagen synthesis in dermal fibroblasts and significantly upregulating the gene and protein expression of Type I/III collagen, elastin, fibronectin, and glycosaminoglycans; while simultaneously promoting the proliferation and differentiation of keratinocytes, strengthening the skin barrier structure, and reducing transepidermal water loss. Consequently, it offers skincare benefits including root-cause anti-aging and wrinkle reduction, barrier repair, repair of photo-damage, and long-lasting hydration. Cosmetics containing this ingredient can improve facial dry lines and fine wrinkles, skin sagging and dehydration, damaged skin barrier, and dullness caused by photoaging, helping the skin regain a firm, plump, and resilient youthful appearance. It is widely used in high-end cosmetics targeting anti-aging, wrinkle reduction, firming and repair, and skin barrier strengthening.
| Product Name | CAS | INCI | |
| Palmitoyl Pentapeptide-4 | 214047-00-4 | Palmitoyl Pentapeptide-4 | |
| Molecular Formula | Molecular Weight | Molecular Structure | |
| C39H75N7O10 | 802.05g/mol |  | |
| Product ID | Specification | Minimal Package | MOQ |
| PMKZ2801 | Purity ≥98.0% | 10g | 10g |