Anti-irritating cosmetics ingredient PMSoothe® Kava97
Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.

Anti-irritating cosmetics ingredient PMSoothe® Kava97
Anti-irritating cosmetics ingredient PMSoothe® Kava97 is a premium active ingredient series developed by Plamed Green Science Group. Derived from natural botanical sources, the products are standardized for highly purified actives and designed to target specific skincare concerns through advanced formulation science.
Introduction
In recent years, the appearance of sensitive skin has become more and more frequent, which significantly affects people’s life quality and increases their psychological pressure and anxiety. Sensitive skin has now become a health issue of global concern. According to the data of China Sensitive Skin Diagnosis and Treatment Expert Consensus, the proportion of Chinese women with sensitive skin is about 36.1%, which means that one out of three people has sensitive skin.

Currently, the mainstream anti-irritation target is TRPV1, while the human body senses external stimuli from the TRPV family, there are six known, from TRPV1 to TRPV6. If the anti-irritation ingredient is only effective on TRPV1, and most likely insensitive to other TRPV receptors, it is not sufficient to comprehensively cover all sources of stimuli to which the skin is subjected. The market needs a new anti-irritant target that not only synergizes with the TRPV1 target, but also inhibits the stimulus signals generated when all TRPV receptors are activated.
Therefore, after many years of in-depth research by Plamed, it was found that Kava Pepper Root Extract is able to directly affect the transmission of stimulus signals-AP generated by the activation of various TRPV receptors through a novel mechanism of action. It has a broader and more reliable anti-irritating effect.

| Product name | PMSoothe® Kava97 |
| INCI name | PIPER METHYSTICUM ROOT EXTRACT, HYDROXYPROPYL CYCLODEXTRIN |
| Actives content | Kavain≥4000ppm Yangonin≥500ppm |
| Solubility | Water-soluble |
| Recommended dosage | 0.1%~2% |
| Function | Anti-irritation |
| Highlights★ | Dual targets anti-irritation(TRPV1 , AP) |